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Porta-cath complicated by IVC thrombosis

Paul Grant1, Robert Insall

  • 1Department of Vascular Surgery, William Harvey Hospital, Ashford, Kent, United Kingdom.

European Journal of Internal Medicine
|June 22, 2005
PubMed

Insights

A patient with acute intermittent porphyria developed inferior vena caval (IVC) thrombosis around their port catheter. This complication precipitated porphyria attacks, preventing prophylactic medication.

Area of Science:

  • Vascular Surgery
  • Hematology
  • Gastroenterology

Background:

  • Port catheters are common for chronic conditions like acute intermittent porphyria (AIP).
  • Inferior vena caval (IVC) thrombosis is a serious complication associated with indwelling venous devices.

Purpose of the Study:

  • To report a case of IVC thrombosis in a patient with AIP using a port catheter.
  • To describe the clinical and pathological findings of this complication.

Main Methods:

  • Observational case report.
  • Review of clinical history and pathological findings.
  • CT contrast studies to visualize thrombosis.

Main Results:

  • A patient with AIP developed IVC thrombosis around an in situ port catheter.
  • The thrombosis extended from below the renal vessels into the iliac veins.
  • The IVC thrombosis precipitated AIP attacks, precluding prophylactic medication.

Conclusions:

  • Port catheter placement can be complicated by IVC thrombosis, even in patients with AIP.
  • IVC thrombosis can precipitate acute intermittent porphyria, posing a significant management challenge.
  • Careful monitoring and consideration of alternative venous access may be warranted in patients with AIP and indwelling catheters.

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