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Primary Burkitt lymphoma of the uterine corpus

C Keller1, D G Savage, M Rusta-Villa

  • 1Department of Pathology, College of Physicians and Surgeons, Columbia University, New York 10032, USA.

Leukemia & Lymphoma
|December 3, 2005
PubMed

Insights

This case study documents the first instance of sporadic Burkitt lymphoma confined to the uterus. The findings highlight that this cancer can appear in unusual locations with varied symptoms.

Area of Science:

  • Oncology
  • Gynecologic Pathology

Background:

  • Sporadic Burkitt lymphoma is an aggressive non-Hodgkin lymphoma.
  • Uterine corpus involvement is exceptionally rare.

Observation:

  • A 40-year-old woman presented with vaginal bleeding.
  • Endometrial biopsy revealed medium-sized lymphocytes consistent with Burkitt lymphoma.
  • Genetic analysis confirmed the characteristic t(8;14) translocation.

Findings:

  • The Burkitt lymphoma was confined to the uterine corpus.
  • No extra-uterine disease was detected.
  • The patient achieved remission after hysterectomy and chemotherapy.

Implications:

  • Burkitt lymphoma can manifest as isolated, organ-confined disease.
  • Unusual presentations and symptoms are possible.
  • This case expands the understanding of lymphoma localization.

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