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Updated: Jul 18, 2026

Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria
Published on: May 25, 2022
The association between copper containing IUCD and bacterial vaginosis
Sayeste Demirezen1, Ayşegül Küçük, M Sinan Beksaç
1Hacettepe University, Faculty of Science, Department of Biology, 06532, Ankara, Turkey. sayeste@hacettepe.edu.tr
Insights
This study found a significant link between bacterial vaginosis (BV) and long-term intrauterine contraceptive device (IUCD) use. Limiting IUCD use to under five years and regular check-ups may help prevent BV.
Area of Science:
- Gynecology
- Microbiology
- Public Health
Background:
- Bacterial vaginosis (BV) is a common vaginal condition.
- Intrauterine contraceptive devices (IUCDs) are widely used for birth control.
Purpose of the Study:
- To investigate the association between bacterial vaginosis (BV) and the use of intrauterine contraceptive devices (IUCDs).
Main Methods:
- Cytological analysis of 600 Papanicolaou-stained cervicovaginal smears.
- Statistical analysis to determine the correlation between IUCD use and BV presence.
Main Results:
- A significant correlation (p < 0.05) was found between IUCD use and the presence of BV.
- BV was detected in 7.1% of IUCD users compared to 1.8% of non-users.
- Long-term IUCD use (over 4 years) was associated with BV in most positive cases.
Conclusions:
- Long-term IUCD use is significantly associated with an increased risk of bacterial vaginosis.
- Periodic microscopic examinations and limiting IUCD use to less than five years are recommended to prevent BV.
Abstract:
This study was designed to investigate whether there is an association between bacterial vaginosis (BV) and the use of intrauterine contraceptive device (IUCD). Six hundred Papanicolaou stained cervicovaginal smears were analyzed cytologically. 56 of 600 patients (9.3%) were detected as having IUCD. Four of 56 (7,1%) and 10 of 544 (1.8%) were positive for BV [Bv (+)]. The duration of the use of IUCD was higher than 4 years in 3 of 4 patients who were BV (+). This study showed a significant correlation between the use of IUCD and the presence of BV statistically (p < 0.05). Our findings also suggest that time limited BV infection is associated with long term use of this device. It can be suggested that a periodic microscopic examination and use of IUCD (less than 5 years) are convenient to prevent this kind of anaerobic infection.
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