Application of interferons in the control of infectious diseases of cattle

L A Babiuk1, L M Sordillo, M Campos

  • 1Veterinary Infectious Disease Organization, Saskatoon, SK, Canada.

Journal of Dairy Science
|December 1, 1991
PubMed

Insights

Interferons show potential in reducing cattle diseases like bovine respiratory disease and mastitis by modulating immune responses. Further research is needed to overcome challenges for their widespread clinical application.

Area of Science:

  • Veterinary Immunology
  • Infectious Disease Research
  • Cytokine Therapeutics

Background:

  • Immune system recovery from infection relies on cell interactions mediated by cytokines.
  • Cytokines activate immune cells to combat pathogens, influencing disease progression.

Purpose of the Study:

  • To review the application of interferons in managing bovine respiratory disease and mastitis.
  • To discuss the potential and limitations of using interferons for disease modulation in cattle.

Main Methods:

  • Review of existing literature on interferon applications in veterinary medicine.
  • Analysis of in vitro and in vivo studies investigating cytokine mechanisms.

Main Results:

  • Interferons can reduce morbidity and mortality in cattle affected by specific infections.
  • The review highlights the therapeutic potential of interferons in veterinary contexts.

Conclusions:

  • Interferons represent a promising therapeutic avenue for bovine respiratory disease and mastitis.
  • Obstacles to the clinical use of interferons in cattle require further investigation and resolution.

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