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Lymphatic vessels in human sural nerve: immunohistochemical detection by D2-40
1Department of Biomedical Sciences, Section of Anatomy and Histology, University of Siena, Italy. volpi@unisi.it
Lymphology
|February 27, 2007
Insights
Lymphatic vessels were identified in the human sural nerve
Area of Science:
- Neuroscience
- Vascular Biology
- Anatomy
Background:
- The lymphatic system's role in peripheral nerves is not fully understood.
- Previous studies have primarily focused on central nervous system lymphatics.
Purpose of the Study:
- To investigate the presence and location of lymphatic vessels within the human sural nerve epineurium.
Main Methods:
- Immunohistochemistry using D-240 antibody.
- Ultrastructural examination via electron microscopy.
Main Results:
- D-240 immunostaining revealed positive signals in the epineurium.
- Ultrastructural analysis confirmed the presence of lymphatic endothelial cells and associated structures.
Conclusions:
- Lymphatic vessels are present in the epineurium of the human sural nerve.
- This finding contributes to understanding neuro-lymphatic interactions in peripheral nerves.
Abstract:
Lymphatics were detected in the epineurium of the human sural nerve by D-240 immunostaining and confirmed by ultrastructural examination.
