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[Canine lymphadenitis caused by Cryptococcus neoformans. First case in Chile]

Pamela Thomson1, Gabriel Miranda, Víctor Silva

  • 1Programa de Microbiología y Micología, ICBM, Facultad de Medicina, Universidad de Chile, Independencia 1027, Santiago, Chile.

Revista Iberoamericana De Micologia
|March 29, 2007
PubMed

Insights

This study details the first canine cryptococcosis case in Chile, caused by Cryptococcus neoformans affecting lymph nodes. Treatment with ketoconazole led to a full recovery, with no recurrence two years later.

Area of Science:

  • Veterinary Mycology
  • Infectious Diseases

Background:

  • Cryptococcosis is a fungal infection that can affect animals and humans.
  • Canine cryptococcosis is rare, with limited case reports globally.

Observation:

  • A Rottweiler dog in Chile presented with generalized lymphadenomegaly affecting multiple lymph nodes.
  • Biopsies confirmed the presence of Cryptococcus neoformans in affected lymph node tissue.

Findings:

  • The canine patient was successfully treated with oral ketoconazole over six months.
  • The dog showed complete clinical improvement and remained infection-free two years post-treatment.

Implications:

  • This case highlights the potential for Cryptococcus neoformans to cause lymphadenomegaly in dogs in Chile.
  • Effective antifungal treatment protocols can lead to favorable outcomes in canine cryptococcosis.
  • Further surveillance for fungal infections in veterinary patients is warranted.

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