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Published on: February 12, 2022

Primary diffuse large B-cell lymphoma of the testis: a case-report

Maria Gaetana Lamendola1, Franca Ferraraccio, Umberto Pane

  • 1Istituto di Anatomia Patologica, Seconda Università degli Studi, Napoli, Italy.

Archivio Italiano Di Urologia, Andrologia : Organo Ufficiale [Di] Societa Italiana Di Ecografia Urologica E Nefrologica
|May 9, 2007
PubMed

Insights

A rare case of primary non-Hodgkin lymphoma of the testis, specifically diffuse large B-cell lymphoma, was diagnosed in a 74-year-old man presenting with testicular swelling. This highlights the importance of considering lymphoma in testicular masses.

Area of Science:

  • Oncology
  • Pathology

Background:

  • Primary non-Hodgkin lymphoma of the testis is a rare malignancy.
  • Testicular swelling can be indicative of various conditions, including malignancy.

Observation:

  • A 74-year-old male presented with a one-month history of testicular swelling.
  • Physical examination revealed testicular enlargement, prompting further investigation.

Findings:

  • Light microscopy confirmed diffuse large B-cell lymphoma involving the epididymis, rete testis, and testicular parenchyma.
  • Immunohistochemistry showed tumor cells positive for CD45, CD20, and Ki67.

Implications:

  • This case underscores the need for thorough diagnostic evaluation of testicular masses.
  • Understanding the clinical and pathological features of primary testicular lymphoma is crucial for appropriate management.

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