Related Experiment Video

Updated: Jul 14, 2026

Collection, Isolation, and Flow Cytometric Analysis of Human Endocervical Samples
12:34

Collection, Isolation, and Flow Cytometric Analysis of Human Endocervical Samples

Published on: July 6, 2014

Cervical intraepithelial neoplasia in Jordan: A ten year retrospective cytoepidemiologic study

Y F Dajani1, U M Maayta, Y R Abu-Ghosh

  • 1Consulting Medical Laboratories, Amman, Jordan.

Annals of Saudi Medicine
|July 1, 1995
PubMed

Insights

Cervical intraepithelial neoplasia (CIN) occurred in 1.1% of females in Jordan. Papanicolaou (Pap) smears are valuable for detecting CIN in Jordanian women over 20, particularly those over 35.

Area of Science:

  • Gynecology
  • Oncology
  • Public Health

Background:

  • Cervical intraepithelial neoplasia (CIN) is a significant public health concern.
  • Understanding the epidemiology of CIN in different regions is crucial for targeted screening and prevention strategies.
  • Previous data on CIN occurrence in Jordan was limited.

Purpose of the Study:

  • To determine the frequency and incidence of CIN in females attending obstetric and gynecology clinics in Jordan.
  • To analyze the grading of CIN cases and their correlation with cytological findings.
  • To identify potential risk factors associated with CIN occurrence in the Jordanian population.

Main Methods:

  • A retrospective study of 10,659 females attending obstetric and gynecology clinics in Jordan from 1982 to 1991.
  • Analysis of CIN occurrence, frequency rates, and incidence rates.
  • Histological grading of CIN cases and comparison with cytological results.
  • Investigation of potential associations between CIN and factors such as circumcision of male partners, marital status, age at marriage, parity, breastfeeding, contraceptive pill use, socioeconomic status, and menstrual disorders.

Main Results:

  • The overall frequency of CIN was 1.1% (121 cases) among 10,659 females.
  • The incidence rate in routine check-up attendees was 49 per 100,000 Jordanian females.
  • CIN cases were graded as Grade I (21%), Grade II (48%), and Grade III (31%).
  • Histological grading correlated with cytology in 70% of cases, with 30% showing cytologic underrating.
  • Circumcision in male partners and marital status were associated with a lower frequency of CIN.
  • No significant relationship was found between CIN frequency and age at marriage, parity, breastfeeding, contraceptive pill use, socioeconomic status, or menstrual disorders.

Conclusions:

  • CIN occurrence in Jordanian females is substantial, though lower than in high-incidence areas.
  • Papanicolaou (Pap) smears are valuable for detecting CIN in Jordanian females over 20, especially those over 35 attending gynecological clinics.
  • Further studies are needed to determine the incidence of CIN in the general female population in Jordan.

More Related Videos

Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia03:05

Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia

Published on: February 16, 2024

Related Concept Videos

Cellular Adaptation IV: Dysplasia and Metaplasia01:24

Cellular Adaptation IV: Dysplasia and Metaplasia

DysplasiaDysplasia refers to abnormal changes in the size, shape, and organization of mature cells, characterized by pleomorphism, nuclear abnormalities, and increased mitotic activity. It commonly affects epithelial tissues, including the cervix, gastrointestinal tract, respiratory mucosa, and endometrium. Although it may occur alongside hyperplasia, dysplasia is not a true adaptive response but a preneoplastic change with potential to progress to cancer.When confined above the basement...
Prevalence and Incidence01:08

Prevalence and Incidence

In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health condition at a...
Non-LTR Retrotransposons03:18

Non-LTR Retrotransposons

As the name suggests, non-LTR retrotransposons lack the long terminal repeats characteristic of the LTR retrotransposons. Additionally, both LTR and non-LTR retrotransposons use distinct mechanisms of mobilization. Non-LTR retrotransposons are further divided into two classes - Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs), both of which occur abundantly in most mammals, including humans. Some of the active non-LTR retrotransposons in humans are L1...