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Iodide mumps after contrast media imaging: a rare adverse effect to iodine

Yael Gilgen-Anner1, Markus Heim, Hans-Peter Ledermann

  • 1Department of ENT, University Hospital Basel, Basel, Switzerland.

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
|July 27, 2007
PubMed

Insights

Iodide mumps, a rare adverse reaction to iodinated contrast media, caused recurrent salivary gland swelling in a patient undergoing computed tomography. This noninflammatory edema highlights the need to differentiate it from other head and neck swellings.

Area of Science:

  • Radiology
  • Endocrinology
  • Pathology

Background:

  • Iodinated contrast media can cause various adverse reactions, including anaphylactoid and cell-mediated effects.
  • Rare reactions include iodine-related sialadenopathy, iododerma, and acneiform eruptions.

Observation:

  • A patient developed recurrent sublingual gland swellings after contrast-enhanced computed tomography.
  • These swellings, identified as iodide mumps, resolved spontaneously within days.

Findings:

  • Histologic analysis and imaging studies revealed distinct noninflammatory patterns.
  • The reaction was directly linked to iodine exposure from the contrast media.

Implications:

  • Iodide mumps is a rare, noninflammatory salivary gland edema caused by iodinated contrast media.
  • Accurate differentiation from other head and neck swellings is crucial for diagnosis and management.
Abstract

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