B cell lymphoma with unusual clinical cutaneous presentation

Area of Science:

• Dermatology
• Oncology
• Pathology

Background:

• Cutaneous B cell lymphoma (CBCL) is a rare neoplastic proliferation of B lymphocytes in the skin.
• CBCL typically presents as skin plaques or nodules, distinct from T cell lymphomas.
• Unusual presentations of CBCL are infrequently documented in medical literature.

Observation:

• A patient presented with an atypical manifestation of CBCL, characterized by the development of cutaneous horns.
• Cutaneous horns are typically associated with benign or malignant epithelial neoplasms.

Findings:

• The diagnosis of CBCL was confirmed despite the unusual presentation.
• The patient received a treatment regimen combining chemotherapy and localized radiotherapy.
• The patient has remained disease-free for five years post-treatment, indicating successful management.

Implications:

• This case highlights the importance of considering rare presentations in diagnosing CBCL.
• The successful management protocol suggests a viable therapeutic approach for similar rare cases.
• Further research into the diverse clinical manifestations of CBCL is warranted.