Related Experiment Video
Updated: Jul 8, 2026

Murine Bilateral Renal Lymphadenectomy
Published on: December 30, 2025
Primary mucosa-associated lymphoid tissue-type lymphoma arising in the kidney
Yoichiro Kato1, Michihiko Hasegawa, Susumu Numasato
1Departments of Urology and Pathology, Morioka Red Cross Hospital, Morioka, Japan. katouro@morioka.jrc.or.jp
Insights
A rare kidney tumor was identified as mucosa-associated lymphoid tissue (MALT) lymphoma in a young man. This case highlights the importance of accurate diagnosis for this uncommon renal malignancy.
Area of Science:
- Oncology
- Pathology
- Urology
Background:
- Primary renal tumors are uncommon, with renal cell carcinoma being the most frequent. Lymphomas can rarely present as primary renal masses.
- Mucosa-associated lymphoid tissue (MALT) lymphomas typically arise in extranodal sites, and primary renal involvement is exceptionally rare.
Observation:
- A 30-year-old male presented with a right flank abdominal mass detected via ultrasonography.
- Initial diagnosis suggested renal cell carcinoma, leading to radical nephrectomy.
Findings:
- Histopathological examination confirmed the abdominal mass to be a primary low-grade mucosa-associated lymphoid tissue (MALT) lymphoma of the kidney.
- This represents one of only six reported cases of primary renal MALT lymphoma in the medical literature.
Implications:
- Accurate preoperative diagnosis is crucial for appropriate management of rare renal masses.
- Surgical resection is the primary treatment modality for primary renal MALT lymphoma, with limited need for adjuvant chemotherapy in reported cases.
Abstract:
We report a case of primary low-grade lymphoma of mucosa-associated lymphoid tissue (MALT) arising from the kidney in a 30-year-old man with an abdominal mass in the right flank detected by ultrasonography. Radical nephrectomy was performed under a preliminary diagnosis of renal cell carcinoma. The final histological diagnosis was MALT-type lymphoma. To the best of our knowledge, only five reports of primary MALT-type lymphoma in the kidney have been published in the literature so far. All cases were surgically treated and only one case went on to chemotherapy postoperatively.
Related Concept Videos
Secondary Lymphoid Organs
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Lymphoid Cells and Tissues
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Kidney Transplant II: Surgical Procedure
Nephrons
External Anatomy of the Kidney
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
Renal Corpuscle
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous capillaries...