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The prevalence of dementia in an urban Turkish population
1Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Faculty of Medicine, Istanbul University, Capa, Istanbul, Turkey. gurvit@istanbul.edu.tr
Insights
This study found that dementia affects 20% of older adults in Istanbul, with Alzheimer's disease (AD) accounting for 11%. These prevalence rates for dementia and AD are similar to those reported in Western countries.
Area of Science:
- Gerontology
- Neurology
- Epidemiology
Background:
- Cognitive impairment and dementia are significant public health concerns in aging populations worldwide.
- Understanding the prevalence of dementia and Alzheimer's disease (AD) in diverse geographical regions is crucial for resource allocation and intervention planning.
Purpose of the Study:
- To determine the prevalence of dementia and probable Alzheimer's disease (AD) in community-dwelling individuals aged 70 years and older in Istanbul, Turkey.
- To compare these prevalence rates with those reported in Western populations.
Main Methods:
- A population-based, two-stage cross-sectional study was conducted with 1019 participants aged 70+ in Istanbul.
- The Mini-Mental State Examination (MMSE) was used for initial cognitive screening, followed by a standardized diagnostic workup for those screening positive.
- Dementia and probable AD diagnoses were established using established diagnostic criteria.
Main Results:
- The prevalence of dementia was 20.0% (95% CI, 14.0% to 26.0%), and the prevalence of probable Alzheimer's disease (AD) was 11.0% (95% CI, 7.0% to 15.0%).
- A total of 93 dementia cases were identified, with 58 diagnosed as probable AD.
- The study included 322 individuals who screened positive on the MMSE and 63 who screened negative.
Conclusions:
- The prevalence rates of dementia and probable AD in Istanbul are comparable to those observed in Western countries.
- These findings highlight the significant burden of dementia in the Turkish elderly population.
- Further research is warranted to explore contributing factors and develop targeted interventions for dementia prevention and management in this region.
Abstract:
A cross-sectional, population-based, 2-stage prevalence study was conducted in a sample of 1019 community-dwelling persons over the age of 70 years living in Istanbul. In the first phase, participants were screened with the Mini-Mental State Examination for evidence of cognitive impairment. In the second phase, 79% of those who screened positive (n = 322) and 9% of screen-negatives (n = 63) underwent a standardized diagnostic workup. Diagnosis of dementia and Alzheimer's disease (AD) was made according to established criteria. Ninety-three cases of dementia were identified, 58 of whom were diagnosed with probable AD. Based on these numbers, the prevalence rates of probable AD and dementia were calculated to be 11.0% (95% CI, 7.0% to 15.0%) and 20.0% (95% CI, 14.0% to 26.0%), respectively, in this population. Prevalence rates of dementia and AD in Istanbul, Turkey, are comparable with those seen in the Western world.
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