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Ultrasonographic Evaluation of Salivary Glands for Sjogren's Syndrome: Diagnostic and Monitoring Insights
Published on: October 13, 2023
A lady with rapid onset of swollen parotid glands
Kai Ming Chow1, Ka Tak Wong, Cheuk Chun Szeto
1Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, China. chow_kai_ming@alumni.cuhk.net
Insights
Iodide mumps, a salivary gland swelling, can occur after iodinated contrast media. Renal impairment increases vulnerability, and recurrence is common with repeat contrast exposure.
Area of Science:
- Radiology and Imaging
- Nephrology
- Endocrinology
Background:
- Iodide mumps is an acute salivary gland swelling occurring after iodinated contrast media administration.
- The condition is linked to iodide accumulation in salivary glands, particularly with certain contrast preparations.
- Renal impairment is a potential risk factor, prolonging contrast media's half-life and increasing iodide exposure.
Purpose of the Study:
- To present a case of iodide mumps.
- To discuss the role of renal impairment in iodide mumps.
- To review the literature on iodide mumps and its management.
Main Methods:
- Case report presentation.
- Literature review of 30 previously published cases of iodide mumps.
- Analysis of patient data focusing on contrast media exposure and renal function.
Main Results:
- Iodide mumps can occur with any osmolality of iodinated contrast media.
- Renal impairment significantly increases the risk and duration of contrast media effects.
- Conservative management is typically effective for resolving iodide mumps.
Conclusions:
- Iodide mumps is a recognized complication of iodinated contrast media.
- Patients with renal impairment are particularly vulnerable to this condition.
- Recurrence of iodide mumps is likely if vulnerable patients receive further iodinated contrast media.
Abstract:
Iodide mumps can occur after administration of any iodinated contrast media, irrespective of the osmolality of the contrast preparation. This condition is characterized by acute salivary gland swelling shortly after contrast study, presumably secondary to toxic accumulation of iodide in salivary glands with high iodide concentration. In this article, a case of iodide mumps is presented, along with a discussion of vulnerability due to renal impairment, which causes prolongation of the half-life of contrast media. A total of 30 additional cases of iodide mumps published in the English literature were reviewed. Despite the clinical observations that iodide mumps resolved with conservative management, it should be emphasized that recurrence is common if vulnerable patients are subjected to further iodinated contrast media.
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