A lady with rapid onset of swollen parotid glands

Kai Ming Chow1, Ka Tak Wong, Cheuk Chun Szeto

  • 1Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, China. chow_kai_ming@alumni.cuhk.net

Insights

Iodide mumps, a salivary gland swelling, can occur after iodinated contrast media. Renal impairment increases vulnerability, and recurrence is common with repeat contrast exposure.

Area of Science:

  • Radiology and Imaging
  • Nephrology
  • Endocrinology

Background:

  • Iodide mumps is an acute salivary gland swelling occurring after iodinated contrast media administration.
  • The condition is linked to iodide accumulation in salivary glands, particularly with certain contrast preparations.
  • Renal impairment is a potential risk factor, prolonging contrast media's half-life and increasing iodide exposure.

Purpose of the Study:

  • To present a case of iodide mumps.
  • To discuss the role of renal impairment in iodide mumps.
  • To review the literature on iodide mumps and its management.

Main Methods:

  • Case report presentation.
  • Literature review of 30 previously published cases of iodide mumps.
  • Analysis of patient data focusing on contrast media exposure and renal function.

Main Results:

  • Iodide mumps can occur with any osmolality of iodinated contrast media.
  • Renal impairment significantly increases the risk and duration of contrast media effects.
  • Conservative management is typically effective for resolving iodide mumps.

Conclusions:

  • Iodide mumps is a recognized complication of iodinated contrast media.
  • Patients with renal impairment are particularly vulnerable to this condition.
  • Recurrence of iodide mumps is likely if vulnerable patients receive further iodinated contrast media.

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