Related Experiment Video
Updated: Jun 24, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Childhood asymmetric labium majus enlargement: is a conservative approach available?
Tutku Soyer1, Oymen Hançerlioğullari, Aylin Pelin Cil
1Department of Pediatric Surgery, Kirikkale University, Turkey. tutku@sanalofis.net
Insights
Childhood asymmetric labium majus enlargement is a rare condition causing unilateral vulva swelling in prepubertal girls. This case highlights its benign nature and the benefits of a conservative treatment approach.
Area of Science:
- Pediatric Gynecology
- Dermatology
- Surgical Pathology
Background:
- Unilateral vulva swelling in prepubertal children can stem from diverse inflammatory and neoplastic causes.
- Distinguishing benign conditions from more serious pathologies is crucial for appropriate management.
Observation:
- A case of childhood asymmetric labium majus enlargement in an 11-year-old girl is presented.
- This condition involves labial enlargement with normal radiologic, histopathologic, and surgical findings.
Findings:
- Childhood asymmetric labium majus enlargement represents a rare, benign entity.
- Clinicopathologic features and differential diagnoses are discussed.
Implications:
- The findings support a conservative management strategy for this rare condition.
- Accurate diagnosis is key to avoiding unnecessary interventions in pediatric vulvar conditions.
Abstract:
Unilateral vulva swelling during prepubertal period consists of a wide variety of inflammatory and neoplastic lesions. A group of labial lesions that showed normal radiologic, histopathologic and surgical findings are reported as childhood asymmetric labium majus enlargement. An 11-year-old girl with childhood asymmetric labium majus enlargement is presented to discuss the clinicopathologic features, differential diagnosis, and indications of conservative approach in the treatment of this rare entity.