Related Experiment Video

Updated: Jun 13, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
07:36

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

[Pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma accompanied with cystic change]

Itaru Nagahiro1, Hiroshi Nouso, Tsuyoshi Kawai

  • 1Department of Surgery, Himeji Red Cross Hospital, Himeji, Japan.

Kyobu Geka. the Japanese Journal of Thoracic Surgery
|April 15, 2010
PubMed

Insights

A 64-year-old male presented with throat discomfort and was diagnosed with primary lung mucosa-associated lymphoid tissue (MALT) lymphoma. Surgical resection was successful, highlighting a rare cystic presentation of pulmonary MALT lymphoma.

Area of Science:

  • Pulmonology
  • Oncology
  • Pathology

Background:

  • Primary pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma is a rare extranodal non-Hodgkin lymphoma.
  • MALT lymphomas typically arise in extranodal sites, with pulmonary involvement being uncommon.

Observation:

  • A 64-year-old male presented with throat discomfort.
  • Chest computed tomography (CT) revealed a cystic lesion with a central solid component in the right lower lobe (4.1 x 3.9 cm).

Findings:

  • Transbronchial lung biopsy diagnosed the lesion as MALT lymphoma of the lung.
  • The patient was diagnosed with stage I-E MALT lymphoma.
  • A right lower lobectomy was performed, and the cystic lesion was attributed to lymphoma infiltration causing air retention via a check-valve mechanism.

Implications:

  • This case highlights a rare cystic presentation of primary pulmonary MALT lymphoma.
  • Early diagnosis and surgical intervention can lead to favorable outcomes.
  • Understanding the pathogenesis of cystic lesions in pulmonary MALT lymphoma is crucial for patient management.

Related Concept Videos

Lymphoid Cells and Tissues01:18

Lymphoid Cells and Tissues

Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Cystic Fibrosis: Pathogenesis01:23

Cystic Fibrosis: Pathogenesis

Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation, but...