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Granular cell tumor--clinically presented as lymphadenopathy
Branka Loncar1, Ksenija Marjanović, Biljana Pauzar
1Department of Clinical Cytology, University Hospital Center Osijek, Osijek, Croatia. loncar.branka@kbo.hr
Insights
Fine needle aspiration cytology can diagnose granular cell tumors, which are rare benign lesions. Surgical excision offers a cure for these tumors, with cytology being the preferred diagnostic method.
Area of Science:
- Oncology
- Cytopathology
- Surgical Pathology
Background:
- Granular cell tumors (GCTs) are uncommon neoplasms with a predilection for soft tissues.
- While typically benign, they can occur in various anatomical locations, presenting diagnostic challenges.
Observation:
- A case of a 25-year-old male with an inguinal mass, initially suspected as lymphadenopathy, is presented.
- Fine needle aspiration (FNA) cytology revealed characteristic polygonal cells with granular cytoplasm and eccentric nuclei.
Findings:
- Cytological findings were consistent with a granular cell tumor.
- Histopathological examination of the surgically excised mass confirmed the diagnosis of benign granular cell tumor.
Implications:
- Fine needle aspiration cytology is a valuable and potentially diagnostic tool for granular cell tumors.
- Complete surgical excision is curative for benign granular cell tumors, highlighting the importance of accurate preoperative diagnosis.
Abstract:
Granular cell tumors are relatively uncommon benign lesions occurring in almost any part of the body. We report the cytological diagnosis of granular cell tumor in 25-year-old male patient who presented with an inguinal mass clinically suspected to be a lymphadenopathy. Fine needle aspiration revealed polygonal cells with abundant, granular cytoplasm and eccentrically located vesicular nuclei and inconspicuous nucleoli. The histopathological examination of the surgical excision confirmed the diagnosis. If resection is complete, local surgical excision is curative for benign granular cell tumors. Granular cell tumor has a characteristic cytological appearance, and fine-needle aspiration cytology has been suggested to be diagnostic modality of choice.
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