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Burkitt's lymphoma: a pericardial presentation
S J Graham1, B Duval-Arnould, T C Mercado
1Department of Laboratory Medicine, National Naval Medical Center, Bethesda, Maryland 20814-5000.
Insights
This case study details childhood Burkitt's lymphoma presenting as a pericardial effusion. Diagnosis was confirmed using cytology, immunophenotyping, and electron microscopy on pericardial fluid.
Area of Science:
- Oncology
- Hematology
- Pediatric Medicine
Background:
- Burkitt's lymphoma is an aggressive non-Hodgkin lymphoma.
- Pericardial effusion is an uncommon presentation in pediatric cancers.
- Early diagnosis is crucial for effective treatment of Burkitt's lymphoma.
Abstract:
Described herein is a case of childhood Burkitt's lymphoma initially presenting as a pericardial effusion. A cytological diagnosis was made from a Wright's-Giemsa stained cytospin preparation. Supporting diagnostic evidence was provided by immunological surface marker analysis and electron microscopy. To our knowledge, Burkitt's lymphoma has not hitherto been diagnosed initially from the morphology of cells in pericardial fluid.
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