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Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells
Published on: August 5, 2016
Brucella canis in a HIV-infected patient
E Lawaczeck1, J Toporek, J Cwikla
1Arizona Department of Health Services, Phoenix, AZ, USA. elisabeth.lawaczeck@state.co.us
Insights
Brucella canis infection in humans is rare, but immunocompromised individuals are at higher risk. This case report details a Brucella canis infection in a patient with human immunodeficiency virus.
Area of Science:
- Veterinary Medicine
- Human Infectious Diseases
- Immunology
Background:
- Brucella canis is a bacterium primarily affecting dogs, with zoonotic potential to humans.
- The incidence of human Brucella canis infections remains largely unquantified.
- Immunocompromised individuals are suspected to be at increased risk of acquiring Brucella canis.
Observation:
- This report describes a case of Brucella canis infection in a human patient.
- The patient was coinfected with human immunodeficiency virus (HIV).
Findings:
- The case highlights a potential link between human immunodeficiency virus and increased susceptibility to Brucella canis.
- This presentation underscores the importance of considering Brucella canis in immunocompromised patients with relevant exposure history.
Implications:
- Further research is needed to elucidate the precise risks and clinical spectrum of Brucella canis in immunocompromised populations.
- Clinicians should maintain a high index of suspicion for Brucella canis in immunocompromised patients, particularly those with canine contact.
- This case emphasizes the One Health approach, recognizing the interconnectedness of animal and human health in infectious disease transmission.
Abstract:
The true incidence of Brucella canis in humans is unknown, but immunocompromised patients in direct contact with dogs are thought to be at a higher risk for infection. In this case report, we present a human case of B. canis in a patient infected with human immunodeficiency virus.
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