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Enterococcus gallinarum meningitis: a case report and literature review
Fahmi Yousef Khan1, Sitina Shamsaldin Elshafi
1Hamad General Hospital, Doha, Qatar. fakhanqal@yahoo.co.uk
Insights
This case study details Enterococcus gallinarum meningitis following surgery. Linezolid effectively treated the infection, leading to patient recovery.
Area of Science:
- Infectious Diseases
- Neuroscience
- Microbiology
Background:
- Meningitis can occur post-neurosurgery.
- Enterococcus gallinarum is an uncommon cause of meningitis.
Observation:
- A 53-year-old female developed fever, headache, and altered consciousness post-craniotomy.
- Cerebrospinal fluid analysis confirmed bacterial meningitis.
- Enterococcus gallinarum was isolated from cerebrospinal fluid.
Findings:
- The Enterococcus gallinarum isolate showed sensitivity to ampicillin, linezolid, and others, but intermediate sensitivity to vancomycin.
- Intravenous linezolid treatment resulted in rapid clinical improvement and cerebrospinal fluid sterilization.
- The patient completed a three-week course of linezolid and was discharged in good condition.
Implications:
- This case highlights the importance of identifying causative agents in post-neurosurgical meningitis.
- Linezolid can be an effective treatment option for Enterococcus gallinarum meningitis, especially in cases with vancomycin intermediate sensitivity.
- Further research into Enterococcus gallinarum meningitis is warranted.
Abstract:
We report a case of Enterococcus gallinarum meningitis in a 53-year-old female who was admitted to our hospital with a fever, headache, and consciousness disturbance one week after a life-saving craniotomy operation. There was obvious neck stiffness; lumber puncture was performed and cerebrospinal fluid parameters were consistent with bacterial meningitis. The patient was given ceftriaxone and vancomycin for bacterial meningitis. Cerebrospinal fluid culture yielded an isolate which was identified as Enterococcus gallinarum. The isolate was sensitive to ampicillin, ampicillin/clavulanate, linezolid, moxifloxacin and teicoplanin, but it showed intermediate sensitivity to vancomycin and quinoprism- dalfopristin. Intravenous linezolid, 600 mg every 12 hours, was started. Three days after starting treatment, the patient became afebrile; a repeat lumber puncture two week later showed no white blood cells in cerebrospinal fluid and no bacterial growth. Treatment with linezolid was continued for a total therapy duration of three weeks, after which the patient was discharged in a good condition.
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