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Primary cutaneous follicle center lymphoma responsive to interferon alfa-2a

Mukaddes Kavala1, Ilkin Zindanci, Sibel Sudogan

  • 1Department of Dermatology, Goztepe Training and Research Hospital, Istanbul, Turkey.

Indian Journal of Dermatology, Venereology and Leprology
|October 22, 2011
PubMed

Insights

Primary cutaneous follicle center lymphoma, a common B-cell malignancy, can occur on the scalp. Treatment with interferon alfa-2a resulted in complete resolution of this rare condition.

Area of Science:

  • Dermatology
  • Oncology
  • Hematology

Background:

  • Follicular lymphoma is the most common primary cutaneous B-cell lymphoma.
  • It typically affects the scalp, forehead, and trunk.

Observation:

  • A case of primary cutaneous follicle center lymphoma on the scalp of a 72-year-old female is presented.
  • Histopathological examination confirmed the presence of centrocytes and centroblasts.

Findings:

  • Complete resolution of the lymphoma was achieved.
  • Treatment involved subcutaneous interferon alfa-2a at a dose of 4.5 × 10⁶ IU, three times weekly for 3 months.

Implications:

  • This case highlights a potential treatment option for primary cutaneous follicle center lymphoma.
  • Early diagnosis and treatment can lead to favorable outcomes for this condition.

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