Multimodality imaging can help to doubt, diagnose and follow-up cardiac mass

Area of Science:

• Cardiology
• Oncology
• Radiology

Background:

• Primary cardiac lymphoma is an extremely rare malignancy primarily affecting the heart.
• Accurate diagnosis and characterization of cardiac masses are crucial for effective treatment.

Purpose of the Study:

• To present two cases of primary cardiac lymphoma.
• To evaluate the utility of various imaging modalities in diagnosing cardiac lymphoma.
• To highlight the role of endomyocardial biopsy in pathological confirmation.

Main Methods:

• Utilized coronary computed tomography angiography (CCTA), cardiac magnetic resonance imaging (CMR), and positron emission tomography (PET) for imaging.
• Performed endomyocardial biopsy under echocardiographic guidance for histopathological confirmation.
• Employed multi-modality imaging for mass characterization and treatment response monitoring.

Main Results:

• Multiple imaging modalities effectively characterized the cardiac mass in both cases.
• Endomyocardial biopsy provided successful pathological confirmation of primary cardiac lymphoma.
• Imaging was instrumental in monitoring the response to chemotherapy.

Conclusions:

• Primary cardiac lymphoma diagnosis benefits from a multi-modality imaging approach.
• Imaging plays a vital role in assessing treatment response in cardiac lymphoma.
• Endomyocardial biopsy remains essential for definitive diagnosis.