Related Experiment Video

Updated: Aug 9, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
10:52

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

[Malignant lymphoma diagnosed by the pericardial biopsy]

Y Hashimoto1, H Fujita, R Sugamura

  • 1First Department of Internal Medicine, School of Medicine, Yokohama City University.

[Rinsho Ketsueki] the Japanese Journal of Clinical Hematology
|September 1, 1990
PubMed

Insights

Malignant lymphoma affecting the heart presented as heart failure and heart block. Gallium scans and pericardial biopsy aided in diagnosing this rare cardiac lymphoma case.

Area of Science:

  • Cardiology
  • Oncology
  • Diagnostic Imaging

Background:

  • Malignant lymphoma involving the pericardium is a rare condition.
  • Cardiac lymphoma can present with diverse and severe cardiovascular symptoms.

Observation:

  • A 69-year-old male presented with heart failure and complete heart block.
  • Imaging revealed significant left pleural effusion and pericardial fluid.
  • Gallium isotope study showed increased uptake in the heart.

Findings:

  • Pericardial biopsy confirmed malignant lymphoma.
  • Chemotherapy led to decreased pleural effusion and normalized gallium uptake.
  • The case highlights diagnostic challenges of antemortem cardiac lymphoma.

Implications:

  • Gallium isotope study is a valuable tool for diagnosing cardiac lymphoma.
  • Pericardial biopsy is crucial for definitive diagnosis.
  • Early diagnosis and treatment can improve outcomes for cardiac lymphoma.

More Related Videos

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients09:16

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients

Published on: February 28, 2018

Three-Dimensional Imaging of Tumor-Bearing Tissue Using the Iterative Bleaching Extends Multiplexity Approach07:16

Three-Dimensional Imaging of Tumor-Bearing Tissue Using the Iterative Bleaching Extends Multiplexity Approach

Published on: April 25, 2025

Related Concept Videos

Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...