Lymphoid hyperplasia detected as a single mass in the gallbladder: report of a case

Satoshi Yamamoto1, Tadashi Tsukamoto, Akishige Kanazawa

  • 1Department of Hepato-Biliary-Pancreatic Surgery, Osaka City General Medical Hospital, 2-13-22 Miyakojima Hondori, Miyakojima-ku, Osaka 534-0021, Japan. satoshi.hbps@gmail.com

Surgery Today
|June 16, 2012
PubMed

Insights

This case report details rare gallbladder lymphoid hyperplasia, presenting unique imaging findings on CT and ultrasound. Diagnosis was confirmed after laparoscopic cholecystectomy, revealing normal lymphocytes and lymph follicles.

Area of Science:

  • Gastroenterology
  • Pathology
  • Radiology

Background:

  • Gallbladder masses require careful differential diagnosis.
  • Lymphoid hyperplasia is an uncommon finding in the gallbladder.

Observation:

  • A 42-year-old female presented with a gallbladder neck mass.
  • Imaging revealed atypical features, and tumor markers were normal.
  • Laparoscopic cholecystectomy was performed due to indeterminate diagnosis.

Findings:

  • Macroscopic examination showed a submural tumor with a clear border.
  • Microscopic analysis identified numerous lymph follicles with germinal centers in the subserosal layer.
  • The final diagnosis was lymphoid hyperplasia with chronic cholecystitis.

Implications:

  • This case highlights the importance of considering rare diagnoses in gallbladder pathology.
  • Unique imaging characteristics of gallbladder lymphoid hyperplasia are presented.
  • Further research may elucidate the pathogenesis and clinical significance of this rare condition.

Related Concept Videos

Gallbladder01:17

Gallbladder

The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins the common...
Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...