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Kimura's disease

S R Ranka1, A Rajput, C V Kantharia

  • 1Dept. of Surgery, Seth G. S. Medical College & K. E. M. Hospital, 400 012, MS Mumbai, India.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
|November 3, 2012
PubMed

Insights

Kimura's disease is a rare condition presenting as a painless neck mass in children. Diagnosis requires suspecting the tetrad of symptoms including eosinophilia and specific antibody levels.

Area of Science:

  • Pediatric Medicine
  • Immunology
  • Pathology

Background:

  • Kimura's disease is a rare, benign inflammatory condition.
  • It typically affects young adults and children, often presenting with a cervical mass.

Purpose of the Study:

  • To highlight the diagnostic challenges and key features of Kimura's disease in a pediatric case.
  • To present a management flowchart based on literature review.

Main Methods:

  • Case report of a 12-year-old child with unilateral cervical mass.
  • Initial investigations were inconclusive, with eosinophilia noted.
  • Diagnosis confirmed via excision biopsy and retrospective analysis.

Main Results:

  • The child presented with a unilateral cervical mass and eosinophilia.
  • Excision biopsy confirmed Kimura's disease.
  • The study emphasizes the diagnostic tetrad: painless unilateral cervical lymphadenopathy, eosinophilia, hyperimmunoglobulin E, and positive Candida antibodies.

Conclusions:

  • Kimura's disease should be considered in pediatric cases with the characteristic tetrad of symptoms.
  • Prompt diagnosis and appropriate management are crucial.
  • A treatment flowchart aids in managing this condition.

Keywords:
Candida specific AntibodiesEosinophiliaKimura’s

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