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Published on: October 14, 2021

A case of leukemia cutis presenting as histiocytoid Sweet's syndrome

Zhang Zhenying1, Liu Xiaoming, Piao Yongjun

  • 1Department of Dermatology, 1st Affiliated Hospital of Dalian Medical University, Dalian, China.

International Journal of Dermatology
|March 5, 2013
PubMed

Insights

Leukemia cutis (LC) can mimic various skin conditions. This case highlights a unique presentation resembling Sweet's syndrome, emphasizing the need for cytologic analysis to differentiate it from histiocytoid Sweet's syndrome.

Area of Science:

  • Dermatology
  • Hematology
  • Pathology

Background:

  • Leukemia cutis (LC) involves leukemic cell infiltration of the skin.
  • LC can clinically resemble numerous dermatological conditions.
  • Differentiating LC from other skin disorders is crucial for accurate diagnosis and treatment.

Observation:

  • A unique case of LC presented with clinical features mimicking Sweet's syndrome.
  • Histopathological examination revealed a histiocytoid Sweet's syndrome manifestation.

Findings:

  • This presentation suggests distinct cutaneous and histopathologic presentations of LC.
  • The histiocytoid variant of Sweet's syndrome may be associated with LC.

Implications:

  • Peripheral blood or bone marrow cytologic analysis is crucial for diagnosing LC, especially when histiocytoid Sweet's syndrome is suspected.
  • Further research is warranted to clarify the relationship between LC and histiocytoid Sweet's syndrome.
Abstract

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