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[Vegetative nervous function and interleukin-2 receptor in patients with vertigo]
1Department of TCM, Sun Yat-Sen University of Medical Science, Guangzhou.
Insights
This study found that vertigo patients exhibit enhanced sympathetic nervous function. Interleukin-2 receptor activity was lower in vertigo patients, suggesting a link between Traditional Chinese Medicine's "Wind" and these physiological changes.
Area of Science:
- Neuroscience
- Immunology
- Traditional Chinese Medicine (TCM)
Context:
- Vertigo is a common condition affecting balance and well-being.
- Sympathetic nervous system function and immune responses are implicated in various health conditions.
- Traditional Chinese Medicine concepts like "Wind" may offer insights into Western medical conditions.
Purpose:
- To investigate the relationship between vegetative nervous function, interleukin-2 receptor activity, and vertigo.
- To explore potential correlations between Traditional Chinese Medicine's "Wind" and physiological markers in vertigo patients.
Summary:
- Wenger's vegetative nervous balance factor analysis revealed enhanced sympathetic nervous function in vertigo patients.
- Interleukin-2 receptor activity, measured by 3H-TdR incorporation, was significantly lower in patients with vertigo compared to controls.
- Lower IL-2 receptor activity was also observed in patients with asthenia syndrome and those with a longer course of illness, independent of sex and age.
Impact:
- Findings suggest a potential link between the TCM concept of "Wind" and heightened sympathetic nervous activity.
- This research may open new avenues for understanding vertigo pathophysiology through an integrated TCM and Western medicine perspective.
- Highlights the role of immune system modulation, specifically IL-2 receptor activity, in vertigo.
Abstract:
The authors used Wenger's vegetative nervous balance factor analysis to measure vegetative nervous function of 75 patients with vertigo revealing enhancement of sympathetic nervous function. The proliferation activity of IL-2 receptor was determined by the amount of 3H-TdR incorporated cpm in the peripheral blood lymphocyte after exogenous IL-2 stimulation (Lymphocult-T). The authors used this technique to measure the activity of IL-2 receptor in 49 patients with hepatitis and vertigo. The results showed that the activity of IL-2 receptor in patients with or without vertigo was lower than the controls (P less than 0.001). And patients with vertigo showed lower activity of IL-2 receptor than that without (P less than 0.01). In these patients with asthenia-syndrome the activity of IL-2 receptor was lower than those with asthenia syndrome. The activity of IL-2 receptor in these patients with long course was lower than those with short course. The difference of sex and age was not significant. The above results suggest that "Wind" in TCM might be related to the enhancement of sympathetic nervous function and the activity of IL-2 receptor.
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