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Castleman's Disease: Unilateral Cervical Involvement and Imaging Findings. A Case Report
N Dogan1, B Hakyemez, N B Topal
1Uludag University Medical School; Bursa, Turkey - bhakyemez@uludag.edu.tr.
Insights
Castleman's disease, a lymph node disorder, can present as a neck tumor. This case highlights its unifocal cervical presentation and differential diagnosis using imaging.
Area of Science:
- Oncology
- Pathology
- Radiology
Background:
- Castleman's disease is a rare lymphoproliferative disorder causing enlarged lymph nodes.
- It commonly affects the mediastinum but can occur in the neck.
- Cervical Castleman's disease is often unifocal and mimics neck tumors.
Purpose of the Study:
- To report a case of unifocal cervical Castleman's disease.
- To discuss its differential diagnosis in the context of cervical tumors.
- To illustrate diagnostic findings using various imaging modalities.
Main Methods:
- Case report of a patient with left-sided cervical Castleman's disease.
- Review of magnetic resonance imaging (MRI) findings.
- Review of computed tomography (CT) findings.
- Review of ultrasonography findings.
Main Results:
- The patient presented with a unifocal mass in the left neck.
- Imaging findings from MRI, CT, and ultrasonography were analyzed.
- Differential diagnostic considerations for cervical tumors were discussed.
Conclusions:
- Unifocal cervical Castleman's disease is a rare entity that requires consideration in the differential diagnosis of neck masses.
- Radiological imaging plays a crucial role in characterizing the lesion and guiding diagnosis.
- Distinguishing Castleman's disease from other cervical tumors is essential for appropriate management.
Abstract:
Castleman's disease is an idiopathic lymphoproliferative disorder characterized by massive enlargement of lymph nodes. It may have a unifocal or multifocal presentation; the mediastinum is the most common site (70%). Patients with cervical disease usually have unifocal involvement (90%). The main problem posed by cervical Castleman's disease is that it should be considered in the differential diagnosis of cervical tumors. This report describes a patient who had unifocal Castleman's disease on the left side of the neck, and discusses the differential diagnosis with findings on magnetic resonance imaging, computed tomography and ultrasonography.
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