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Updated: May 4, 2026
High-frequency Ultrasound Imaging of Mouse Cervical Lymph Nodes
Published on: July 25, 2015
Analysis by high resolution ultrasound of superficial lymph nodes: anatomical, morphological and structural
Stramare Roberto1, Beltrame Valeria1, Del Villano Roberto1
1Department of Medicine, Radiology, University of Padova, Padua, Italy.
Insights
Morphostructural analysis of benign lymph nodes revealed significant variations. Understanding these differences in cervical, axillary, and inguinal lymph nodes is crucial to differentiate normal findings from pathology.
Area of Science:
- Radiology
- Anatomy
- Medical Imaging
Background:
- Lymph nodes are critical components of the immune system.
- Variations in lymph node morphology can impact diagnostic interpretation.
- Understanding benign lymph node morphostructure is essential for accurate clinical assessment.
Purpose of the Study:
- To investigate and analyze the morphostructural variations of benign lymph nodes.
- To compare morphostructural characteristics across different anatomical locations (cervical, axillary, inguinal).
Main Methods:
- Studied 49 cervical, 49 axillary, and 49 inguinal lymph nodes from healthy subjects.
- Evaluated parameters including diameters, axis ratios, hilum and cortex thickness, and echogenicity.
- Assessed the presence of hilum and cortical focal thickening.
Main Results:
- Statistically significant variations were observed in several morphostructural parameters.
- The hilum was identified in 100% of axillary and inguinal lymph nodes, indicating location-specific differences.
- Specific parameters showed significant differences, highlighting distinct morphostructural profiles.
Conclusions:
- Morphostructural differences between lymph node regions are significant.
- These variations must be considered to prevent misinterpretation between physiologic and pathologic lymph nodes (LN).
- Accurate differentiation aids in avoiding misdiagnosis and unnecessary interventions.
Purpose:
To analyze morphostructural variations of benign lymph nodes, 49 cervical , 49 axillary and 49 inguinal lymph nodes had been studied in many healthy subjects.
Methods:
Longitudinal and transverse diameters, longitudinal to transverse axis ratio, hilum and cortex thickness, hilar to cortical thickness ratio, presence and echogenicity of hilum, and presence of cortical focal thickening had been evaluated.
Results:
Some parameters were statistically significant such as for the presence of hilum that was identified in 100% of axillary and inguinal lymph nodes.
Conclusions:
Morphostructural differences must be considered in order to avoid the possible misinterpretation between the physiologic and pathologic LN.
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