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Is single dose povidone iodine sclerotherapy effective in chyluria?

Anil Shrestha1, Parash Mani Shrestha, Rakesh Verma

  • 1Urology Unit, Department of Surgery, Bir Hospital, National Academy of Medical Sciences, Kathmandu, Nepal, anyl77@hotmail.com.

International Urology and Nephrology
|January 15, 2014
PubMed

Insights

Single dose 0.2% povidone iodine renal pelvic instillation sclerotherapy effectively treats chyluria. This safe, day-care procedure avoids continuous catheterization and offers a disease-free duration of 18 months.

Area of Science:

  • Urology
  • Sclerotherapy
  • Nephrology

Background:

  • Chyluria, characterized by milky urine, is often caused by lymphatic system abnormalities.
  • Diagnostic confirmation involves urine analysis for lymphocytes and triglyceride levels.

Purpose of the Study:

  • To assess the efficacy and safety of single-dose 0.2% povidone iodine instillation for chyluria treatment.
  • To evaluate povidone iodine sclerotherapy as a minimally invasive outpatient procedure.

Main Methods:

  • A prospective study included 41 patients with confirmed chyluria.
  • 0.2% povidone iodine solution was instilled into the renal pelvis via ureteric catheter under local anesthesia.
  • Patients were positioned in Trendelenburg during instillation.

Main Results:

  • All 41 patients achieved immediate symptom clearance.
  • Recurrence was observed in 7 patients (17%) with a mean disease-free duration of 18 months.
  • Two patients reported moderate to severe flank pain post-procedure.

Conclusions:

  • Single-dose 0.2% povidone iodine renal pelvic instillation is a safe and effective treatment for chyluria.
  • The day-care nature of this sclerotherapy avoids the need for prolonged ureteral and urethral catheterization.
Abstract

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