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[Management of atypical cervical mycobacteriosis in childhood]
T van Bremen1, E Biesinger, F Göke
1Klinik und Poliklinik für Hals-Nasen-Ohren-Heilkunde/-Chirurgie, Universitätsklinikum Bonn, Bonn, Deutschland, tobias.vanbremen@ukb.uni-bonn.de.
Insights
Atypical mycobacteriosis, a rare cause of cervical lymphadenitis in children, presents as a painless neck mass. Complete surgical excision is the preferred treatment, though evidence from controlled studies is limited.
Area of Science:
- Pediatric Infectious Diseases
- Microbiology
- Surgical Oncology
Context:
- Atypical mycobacteriosis is an uncommon infection affecting cervical lymph nodes in young children.
- It typically manifests as a unilateral, painless neck mass.
- Diagnosis is challenging due to non-specific symptoms and lab findings.
Purpose:
- To review the current understanding and management of atypical mycobacteriosis in pediatric cervical lymphadenitis.
- To discuss various therapeutic strategies, including surgical and non-surgical options.
- To highlight the need for evidence-based treatment guidelines.
Summary:
- Atypical mycobacterial infections are a rare cause of cervical lymphadenitis in immunocompromised children aged 1-5 years.
- The condition usually presents as a painless, unilateral cervical mass, complicating diagnosis and treatment.
- Complete surgical excision is considered the primary treatment, but robust clinical trial data is scarce.
Impact:
- This review aims to guide clinicians in diagnosing and managing pediatric cervical lymphadenitis caused by atypical mycobacteria.
- It underscores the importance of considering this diagnosis in the differential for pediatric neck masses.
- Further research is needed to establish evidence-based therapeutic protocols.
Abstract:
Atypical mycobacteriosis is a rare cause of cervical lymphadenitis that most frequently affects immunoincompetent children between the ages of 12 months and 5 years. The typical clinical manifestation is a painless unilateral cervical mass. The nonspecific clinical symptoms and laboratory parameters complicate diagnosis and, therefore, therapeutic management. Various therapeutic options, including surgery, antimycobacterial drug therapy and wait-and-scan approaches are discussed in the literature. Complete surgical excision has become the established treatment of choice. However, controlled randomized studies that clearly demonstrate the benefits of a particular type of therapy are lacking.
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