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A case of intraventricular primary central nervous system lymphoma

Kimberly Funaro1, Katie C Bailey2, Sadie Aguila2

  • 1Department of Radiology University of South Florida College of Medicine Tampa, FL USA.

Journal of Radiology Case Reports
|June 27, 2014
PubMed

Insights

Primary central nervous system lymphoma rarely presents as multiple intraventricular masses. This case in an immunocompetent adult highlights an unusual manifestation requiring cerebrospinal fluid analysis and biopsy for diagnosis.

Area of Science:

  • Neurology
  • Oncology

Background:

  • Primary central nervous system lymphoma (PCNSL) is a rare non-Hodgkin lymphoma.
  • PCNSL typically originates within the brain, spinal cord, or meninges.
  • Most PCNSL cases present as solitary intracranial masses.

Observation:

  • A 68-year-old immunocompetent male presented with severe headache and unsteady gait.
  • Imaging revealed multiple intraventricular masses.

Findings:

  • Cerebrospinal fluid (CSF) analysis and surgical biopsy confirmed PCNSL.
  • The presentation of multiple intraventricular masses is atypical for PCNSL.

Implications:

  • This case expands the spectrum of clinical and radiological presentations of PCNSL.
  • Highlights the importance of considering PCNSL in the differential diagnosis of intraventricular masses, even with unusual patterns.
  • Emphasizes the diagnostic value of CSF cytology and biopsy in immunocompetent individuals.

Keywords:
Primary CNS lymphomaintraventricular masses

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