Related Experiment Video
Updated: Apr 21, 2026

Identification of Neutrophil Extracellular Traps in Paraffin-Embedded Feline Arterial Thrombi using Immunofluorescence Microscopy
Published on: March 29, 2020
Primary immune-mediated neutropenia in a cat
Carly E Waugh1, Katherine D Scott1, Laura K Bryan1
1Department of Small Animal Clinical Sciences and Department of Veterinary Pathobiology, College of Veterinary Medicine and Biological Sciences, Texas A&M University, College Station, Texas 77843, USA.
Insights
A young cat with persistent neutropenia (low white blood cell count) was diagnosed with an immune-mediated condition. The cat recovered fully after treatment, remaining healthy long-term.
Area of Science:
- Veterinary Medicine
- Immunology
- Hematology
Background:
- Recurrent fever, lethargy, and uveitis are non-specific clinical signs in felines.
- Persistent neutropenia can indicate underlying immune or infectious diseases.
Observation:
- An 18-month-old Himalayan cat presented with recurrent fever, lethargy, and uveitis.
- Diagnostic workup included infectious disease testing and bone marrow cytology.
Findings:
- Primary immune-mediated neutropenia was diagnosed in the feline patient.
- The cat showed a complete clinical recovery following appropriate treatment.
Implications:
- This case highlights the importance of considering immune-mediated neutropenia in young cats with compatible clinical signs.
- Successful treatment led to long-term remission and a normal clinical state without ongoing therapy.
Abstract:
An 18-month-old male castrated indoor Himalayan cat was presented for recurrent fever, lethargy, and uveitis. Persistent neutropenia was identified and tests for infectious disease and bone marrow cytology were performed. Primary immune-mediated neutropenia was diagnosed and successfully treated. At the time of writing this report, 24 mo after the initial diagnosis. the patient was clinically normal and not receiving therapy.

