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An unusual case of disseminated neuroendocrine tumor presenting with generalized lymphadenopathy
K S Karthik1, Hema Kini, Anand U Kini
1Department of General Surgery, Kasturba Medical College, Mangalore, Manipal University, Manipal, Karnataka, India.
Insights
A 64-year-old man with enlarged lymph nodes was initially suspected of having tuberculosis or lymphoma. Further investigation revealed a rare case of disseminated neuroendocrine tumor from an unknown primary source.
Area of Science:
- Oncology
- Pathology
Background:
- Generalized lymphadenopathy is a common clinical presentation.
- Differential diagnoses often include infections like tuberculosis and hematological malignancies such as lymphoma.
Observation:
- A 64-year-old male presented with enlarged lymph nodes in the neck and axillae.
- Routine work-up in India considered tuberculosis and lymphoma.
Findings:
- Fine-needle aspiration cytology (FNAC) results were unexpected.
- Subsequent investigations confirmed disseminated neuroendocrine tumor of unknown primary origin.
Implications:
- Highlights the importance of considering rare diagnoses in cases of generalized lymphadenopathy.
- Underscores the diagnostic challenge posed by neuroendocrine tumors with occult primaries.
Abstract:
A 64-year-old male presented to the surgical out-patient department with multiple enlarged lymph nodes in the neck and axillae. As a routine practice in India, this patient was worked up on the lines of generalized lymphadenopathy with a provisional diagnosis of tuberculosis and lymphoma. The report of fine-needle aspiration cytology (FNAC) came as a surprise and on further work-up it turned out to be that the patient had disseminated neuroendocrine tumor from an unknown primary.
