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Pineal Gland Lymphoma: Case Report and Literature Review
Akshya Gupta1, Mahlon Johnson1, Ali Hussain2
1Department of Radiology, University of Rochester Medical Center, Rochester, New York, USA.
Insights
Primary central nervous system lymphoma is rare, especially in the pineal gland. This case highlights the importance of considering this diagnosis for pineal gland tumors.
Area of Science:
- Neuro-oncology
- Pathology
Background:
- Primary central nervous system (CNS) lymphoma is a rare malignancy.
- Pineal gland tumors are uncommon and present with diverse pathologies.
Observation:
- A 65-year-old male presented with acute headache.
- Imaging revealed a pineal gland mass.
Findings:
- Histopathology confirmed large B cell lymphoma.
- The patient received methotrexate treatment but had a fatal outcome.
Implications:
- Primary CNS lymphoma rarely involves the pineal gland.
- Consider CNS lymphoma in the differential diagnosis of pineal gland masses.
- This case underscores the challenges in treating rare CNS malignancies.
Abstract:
A 65-year-old male presented to our institution with acute-onset headache. Imaging studies demonstrated a mass in the region of the pineal gland, with subsequent histopathology findings being consistent with large B cell lymphoma. The patient was treated with methotrexate, but ultimately did not survive. Primary central nervous system (CNS) lymphoma rarely involves the pineal gland, but should be considered in the differential diagnosis of pineal gland tumors in the appropriate clinical setting.
