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Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
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An Atypical Presentation of Sporadic Jejunal Burkitt's Lymphoma

Pratik Naik1, James Wang2, Michael J Brazeau1

  • 1Department of Internal Medicine, William Beaumont Army Medical Center (WBAMC), 5005 North Piedras Street, El Paso, TX 79920, USA.

Case Reports in Gastrointestinal Medicine
|September 28, 2016
PubMed

Insights

A rare case of primary gastrointestinal lymphoma, Burkitt's lymphoma, was diagnosed in a young male presenting with anemia. Surgical resection followed by chemotherapy led to complete remission.

Area of Science:

  • Oncology
  • Gastroenterology
  • Hematology

Background:

  • Burkitt's lymphoma is an aggressive B-cell non-Hodgkin lymphoma (NHL).
  • Primary gastrointestinal lymphoma is an uncommon presentation.
  • Symptomatic anemia can be an initial indicator of gastrointestinal malignancy.

Purpose of the Study:

  • To report a rare case of jejunal Burkitt's lymphoma presenting as symptomatic anemia.
  • To highlight the diagnostic challenges and successful management of primary gastrointestinal Burkitt's lymphoma.

Main Methods:

  • A 24-year-old male with symptomatic anemia underwent diagnostic evaluations including colonoscopy, EGD, and capsule endoscopy.
  • Push enteroscopy was utilized for tissue biopsy of a jejunal mass.
  • Immunohistochemical stains and PET/CT scan were performed for diagnosis and staging.

Main Results:

  • Capsule endoscopy revealed an ulcerated jejunal mass.
  • Biopsy confirmed Burkitt's lymphoma.
  • PET/CT showed isolated jejunal involvement.
  • The patient achieved complete remission after surgical resection and chemotherapy.

Conclusions:

  • Jejunal Burkitt's lymphoma can present atypically with anemia.
  • Multimodal imaging and endoscopic techniques are crucial for diagnosis.
  • A combined approach of surgical resection and chemotherapy is effective for jejunal Burkitt's lymphoma.

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