Lateral Flow Assay for Interleukin 6: A Technological and Scientific Prospection of a 10-Year Survey

Ingridi de Souza Sene1,2, Vladimir Costa2, Gisele Elias Nunes Pauli3

  • 1Universidade Federal do Piaui, Teresina-PI, Brazil.

Insights

Developing a Lateral Flow Assay (LFA) for Interleukin-6 (IL-6) detection is innovative, with no existing patents found. This biosensor development holds significant biotechnological and economic potential.

Area of Science:

  • Biotechnology
  • Immunotechnology
  • Biosensor Development

Background:

  • Interleukin-6 (IL-6) is a key cytokine implicated in immune responses, cancer, and inflammatory diseases.
  • Quantifying IL-6 is crucial for disease diagnosis and monitoring.
  • Lateral Flow Assays (LFAs) offer a promising platform for IL-6 detection.

Purpose of the Study:

  • To conduct a comprehensive technological and scientific exploration of developing a Lateral Flow Assay (LFA) for Interleukin-6 (IL-6) detection.
  • To assess the novelty and innovation landscape surrounding IL-6 LFAs.

Main Methods:

  • Technological prospection involved patent searches using INPI, Espacenet, and USPTO databases.
  • Scientific investigation utilized Web of Science, Science Direct, PubMed, and Scielo databases from 2007 to May 2017.

Main Results:

  • No patents were identified for IL-6 LFAs, indicating a gap in existing intellectual property.
  • A limited number of scientific articles on IL-6 LFAs were found, highlighting the novelty of this field.
  • The development of an IL-6 LFA presents significant innovation and biotechnological importance.

Conclusions:

  • The development of lateral flow immunosensors for IL-6 is considered innovative due to the absence of relevant patents.
  • While existing research shows promise, current IL-6 detection methods may require external equipment.
  • Future developments aim to create a complete, potentially equipment-free, IL-6 detection system.
Abstract

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