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Published on: May 17, 2019
Mumps presenting with unilateral, synchronous parotid and submandibular gland swelling
Connor Boyle1,2, Panagiotis Asimakopoulos2, Elham Khatamzas3
1Division of Health Sciences, University of Edinburgh, Edinburgh, UK.
Insights
A previously healthy woman presented with unusual unilateral swelling of the parotid and submandibular glands. Despite full immunization, she was diagnosed with mumps virus, highlighting a rare clinical presentation.
Area of Science:
- Infectious Diseases
- Virology
- Immunology
Background:
- Mumps typically presents with bilateral parotid gland swelling.
- Vaccination is highly effective in preventing mumps virus infection.
Observation:
- A 22-year-old woman experienced acute, unilateral facial and neck swelling, fever, and malaise.
- CT imaging revealed synchronous inflammation of both parotid and submandibular glands.
- A PCR swab from the parotid duct confirmed mumps virus.
Findings:
- The patient was fully immunized against mumps.
- No known contact with individuals diagnosed with mumps.
- Unilateral, synchronous parotid and submandibular gland involvement is a rare mumps presentation.
Implications:
- This case suggests mumps can present atypically even in vaccinated individuals.
- Further research may be needed to understand unusual mumps presentations.
- Highlights the importance of considering mumps in differential diagnoses of unilateral facial swelling.
Abstract:
A previously healthy 22-year-old woman presented with acute, unilateral facial and neck swelling, associated with fever and malaise. She was initially treated with intravenous antibiotics; however, CT imaging showed unilateral, synchronous swelling and inflammation of the parotid and submandibular glands, and a PCR swab from the parotid duct was positive for mumps. She was fully immunised and had no contact in the preceding period with anyone diagnosed with mumps. She responded to supportive management and her symptoms resolved over the course of her admission. Unilateral, synchronous swelling and severe inflammation of both the parotid and submandibular glands in mumps is a very unusual presentation, and not one previously reported in the literature.
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