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Dermoscopy findings of a one mm lentigo maligna
Samantha Witta, Andrea Bershow, Ronda S Farah
1Department of Dermatology, University of Minnesota, Minneapolis, Minnesota Department of Dermatology, Minneapolis Veterans Affairs Health Care System, Minneapolis, Minnesota Department of Medicine, University of Minnesota, Minneapolis, Minnesota Department of Medicine, Minneapolis Veterans Affairs Health Care System, Minneapolis, Minnesota. Gold0414@umn.edu.
Insights
Early lentigo maligna (LM) may present as annular-granular structures around a hair follicle. This dermatoscopic finding can aid in the earlier diagnosis of facial lentigo maligna.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Lentigo maligna (LM) is a common form of melanoma in situ, typically affecting sun-damaged skin on the face and neck.
- Early diagnosis of LM is crucial for effective treatment and preventing progression to invasive melanoma.
- The Schiffner progression model describes the evolution of dermatoscopic features in LM.
Observation:
- A 66-year-old man presented with a small, grayish macule on his left cheek.
- Dermatoscopy revealed annular-granular structures surrounding a single hair follicle.
- Histopathology confirmed atypical melanocytes consistent with lentigo maligna.
Findings:
- The observed annular-granular structures surrounding a hair follicle may represent the earliest dermatoscopic sign of lentigo maligna.
- This finding supports the Schiffner progression model, indicating a potential early stage in LM development.
- The case highlights the diagnostic utility of specific dermatoscopic patterns in identifying early-stage facial LMs.
Implications:
- Early recognition of these dermatoscopic features can lead to earlier diagnosis and treatment of lentigo maligna.
- This may improve patient outcomes by reducing the risk of progression to invasive melanoma.
- Clinicians should consider these findings when evaluating suspicious pigmented lesions on the face.
Abstract:
A 66-year-old man presented with a grayish 1mm macule on the left cheek. Dermatoscopic examination revealed annular-granular structures partially surrounding a single follicular ostium. Histopathologic examination demonstrated atypical, confluent single melanocytes at the basal layer with nesting, crowding, and upward migration descending along the hair follicle, consistent with the diagnosis of lentigo maligna (LM). This case presents evidence in support of the Schiffner progression model for LMs, starting with asymmetric pigmented follicular openings composed of annular-granular structures, which later coalesce into gray to dark black/brown streaks, and then form pseudo-networks or rhomboidal structures. The finding of annular-granular structures partially surrounding a single hair follicle may be the earliest recognizable dermatoscopic feature of an LM and may help clinicians diagnose facial LMs earlier.
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