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Updated: Jan 29, 2026

Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function
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Use of Fluorodeoxyglucose-Positron Emission Tomography in the Diagnosis of Intravascular Diffuse Large B-Cell

Kristen Tobin-Vealey1, Shikha Jain1, Sameer Al Diffalha1

  • 1is a resident in internal medicine; is a fellow in hematology/oncology; is a resident in pathology; is a resident in radiology; is an assistant professor of medicine and a hematologist/oncologist; is an assistant professor of medicine and a hematologist/oncologist, all at Loyola University Medical Center in Maywood, Illinois. is a hematologist/oncologist and professor of medicine at the Hines VA Medical Center in Hines, Illinois.

Federal Practitioner : for the Health Care Professionals of the VA, Dod, and PHS
|February 16, 2019
PubMed

Insights

Diagnosing intravascular large B-cell lymphoma is challenging early on. Fluorodeoxyglucose-positron emission tomography (FDG-PET) scans can help speed up diagnosis for this rare cancer.

Area of Science:

  • Oncology
  • Medical Imaging

Background:

  • Intravascular large B-cell lymphoma (IVLBL) presents diagnostic difficulties, especially in initial disease phases.
  • Early detection is crucial for effective treatment of IVLBL.

Purpose of the Study:

  • To evaluate the utility of fluorodeoxyglucose-positron emission tomography (FDG-PET) in the timely diagnosis of intravascular large B-cell lymphoma.

Main Methods:

  • Review of diagnostic approaches for IVLBL.
  • Analysis of FDG-PET scan findings in confirmed IVLBL cases.

Main Results:

  • FDG-PET imaging can reveal characteristic patterns suggestive of IVLBL.
  • The use of FDG-PET may shorten the diagnostic timeline compared to conventional methods.

Conclusions:

  • FDG-PET is a valuable tool for improving the diagnostic speed of intravascular large B-cell lymphoma.
  • Integrating FDG-PET into diagnostic workups can aid clinicians in identifying IVLBL earlier.

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