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Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
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Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

Published on: February 9, 2024

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Iodine concentration and content measured by dual-source computed tomography are correlated to thyroid hormone levels

Zheng-Teng Li1, Rui Zhai1, Hong-Mei Liu1

  • 1Department of Radiology, Jining No.1 People's Hospital, Jining, 272000, China.

BMC Medical Imaging
|February 2, 2020
PubMed

Insights

Dual energy CT can measure thyroid iodine content, correlating with thyroid function. This method helps assess iodine nutritional status and thyroid health, aiding disease diagnosis and treatment.

Area of Science:

  • Radiology
  • Endocrinology
  • Nuclear Medicine

Background:

  • Assessing thyroid function and iodine status is crucial for diagnosing and managing thyroid diseases.
  • Dual-energy CT (DECT) offers a non-invasive method to quantify iodine concentration within thyroid tissue.
  • Understanding the relationship between DECT-measured iodine and thyroid hormone levels is essential for clinical application.

Purpose of the Study:

  • To investigate the correlation between dual energy CT (DECT) measured iodine concentration and total iodine content in the thyroid.
  • To examine the relationship between these DECT-derived iodine metrics and blood-measured thyroid parameters.

Main Methods:

  • A retrospective study included 43 patients with normal thyroid function.
  • DECT scans of the neck were performed to measure mean iodine concentration and thyroid tissue volume.
  • Total iodine content was calculated, and correlations with thyroid hormones (FT3, TT3, TT4, FT4, TSH) were analyzed.

Main Results:

  • Total thyroid iodine content showed a positive correlation with triiodothyronine (FT3) and a negative correlation with thyroid-stimulating hormone (TSH).
  • Mean iodine concentration in the thyroid was positively correlated with both FT3 and total triiodothyronine (TT3).

Conclusions:

  • DECT-measured thyroid iodine content can serve as an indicator of iodine nutritional status.
  • This imaging technique can aid in evaluating thyroid function and facilitate the diagnosis and treatment of thyroid diseases.
Abstract

Keywords:
Dual energy CTIodine concentrationThyroid

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