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Reduction in Baseline CD4 Count Testing Following Human Immunodeficiency Virus "Treat All" Adoption in Uganda

Esther Nasuuna1, Mark W Tenforde2,3, Alex Muganzi1

  • 1Infectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|May 7, 2020
PubMed

Insights

CD4 testing rates in Uganda dropped significantly after the "Treat All" policy. Many patients still present with advanced HIV disease, indicating a critical gap in care despite policy changes.

Area of Science:

  • Public Health
  • Infectious Diseases
  • HIV/AIDS Research

Background:

  • The

Purpose of the Study:

  • To analyze trends in CD4 testing rates and the prevalence of advanced HIV disease in Uganda following the

Main Methods:

  • Retrospective analysis of CD4 testing data and patient demographics.
  • Examination of HIV disease staging at the time of diagnosis or testing.

Main Results:

  • CD4 testing rates decreased from 73% in 2013 to 21% in 2018.
  • In 2018, 24% of tested individuals had advanced HIV disease (CD4 < 200 cells/µL).
  • 83% of those with advanced disease presented with WHO stage I/II disease.

Conclusions:

  • A dramatic decline in CD4 testing occurred despite the

Keywords:
CD4HIVopportunistic infectionstest-and-treattreat all

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