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Published on: April 12, 2024
Eccrine angiomatous hamartoma: First case in the cytology literature
U Salma Nisar1, Lori A Erickson2, Andrew L Folpe2
1Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, USA.
Insights
A rare eccrine angiomatous hamartoma, a mixed epithelial and mesenchymal proliferation, was diagnosed in a 34-year-old male. This case is the first to detail the cytomorphologic features of this unusual hand swelling.
Area of Science:
- Dermatopathology
- Surgical Pathology
- Hand Surgery
Background:
- Eccrine angiomatous hamartoma is a rare benign proliferation of sweat gland (eccrine) and vascular components.
- These lesions typically present as cutaneous nodules, often on the extremities.
- Diagnosis can be challenging due to their rarity and variable presentation.
Abstract:
A 34-year-old male presented with a swelling on the volar surface of the third digit of his right hand. This swelling was associated with pain and erythema. Ultrasound-guided needle biopsy was performed. Cytologic and histologic preparations together confirmed the diagnosis of a rarely encountered mixed epithelial and mesenchymal proliferation, an eccrine angiomatous hamartoma. To our knowledge, this case is the first to illustrate the cytomorphologic features of this rare lesion.

