The importance in early identification of a herpetic endobronchial mass

Spandana Narvaneni1, Anish Samuel1, Rajapriya Manickam1

  • 1St. Joseph's University Medical Center, United States.

Insights

A rare case of Herpes Simplex Virus (HSV) I and II endobronchial mass caused respiratory failure in a 78-year-old female. This highlights the importance of considering HSV in endobronchial mass differentials for prompt diagnosis and treatment.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Oncology

Background:

  • Endobronchial masses can cause significant respiratory compromise.
  • Herpes Simplex Virus (HSV) is an uncommon cause of endobronchial obstruction.

Observation:

  • A 78-year-old female presented with hypercapnic, hypoxic respiratory failure requiring intubation.
  • An obstructing mass in the right main stem bronchus was identified.

Findings:

  • Biopsy and immunohistochemistry (IHC) confirmed the mass was positive for Herpes Simplex Virus (HSV) I and II.
  • This represents a rare instance of a herpetic endobronchial mass.

Implications:

  • Including HSV in the differential diagnosis for endobronchial masses is crucial, especially in intubated patients.
  • Prompt diagnosis of herpetic endobronchial masses can lead to timely treatment and potentially reduce unnecessary investigations.

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