Related Experiment Video
Updated: Oct 12, 2025

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
Primary Cardiac Lymphoma: A Case Report
Firas Ajam1, Priyanka Batchu1, Kyle Wiseman2
1Cardiology Department, Jersey Shore University Medical Center, Neptune, NJ, USA.
Insights
This case report details a rare cardiac lymphoma in a 61-year-old male. Treatment led to significant clinical and echocardiographic improvement, highlighting successful management of this unusual heart tumor.
Area of Science:
- Cardiology
- Oncology
- Pathology
Background:
- Cardiac lymphoma is an exceptionally rare malignancy affecting the heart or pericardium.
- It predominantly occurs in individuals with compromised immune systems.
Observation:
- A 61-year-old male presented with dyspnea and substantial weight loss.
- Imaging revealed a right-sided cardiac tumor with interatrial septal perforation and left atrial enlargement.
Findings:
- Diagnosis was confirmed via mediastinal mass biopsy.
- The patient demonstrated clinical improvement and positive transesophageal echocardiography results post-treatment.
Implications:
- This case underscores the importance of considering rare cardiac neoplasms in differential diagnoses.
- Successful treatment outcomes are achievable even with advanced cardiac involvement.
Abstract:
Cardiac lymphoma is a rare neoplasm involving heart, pericardium or both, usually seen in immunocompromised patients. We report a 61-year-old male presenting with worsening shortness of breath and 20-pound weight loss. Investigations showed right-sided tumor with interatrial septal wall perforation and left atrial expansion. The diagnosis was confirmed with mediastinal mass biopsy. After receiving the appropriate treatment, there was a steady improvement clinically and on the transesophageal echocardiography.

