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Updated: Oct 9, 2025
Intravital Imaging of Intraepithelial Lymphocytes in Murine Small Intestine
Published on: June 24, 2019
Ileal plasmablastic lymphoma presenting as intestinal occlusion in an HIV-negative patient with chronic lymphocytic
Luis Figuero-Pérez1, Alejandro Olivares-Hernández2, Marta Navalón-Jiménez2
1Medical Oncology, Hospital Universitario de Salamanca, España.
Insights
A 56-year-old male with chronic lymphocytic leukemia (CLL) presented with abdominal pain and constipation. Imaging revealed a small bowel obstruction caused by a proximal ileal neoplasm.
Area of Science:
- Gastroenterology
- Hematology
- Oncology
Background:
- Chronic lymphocytic leukemia (CLL) is a common lymphoid malignancy.
- Patients with CLL may present with various complications.
- Therapeutic abstention is a management strategy for early-stage CLL.
Observation:
- A 56-year-old male with early-stage CLL presented with a two-week history of low abdominal pain and constipation.
- Physical examination revealed mild diffuse abdominal pain.
- Laboratory findings included lymphocytosis and anemia.
Findings:
- Abdominal computed tomography (CT) scan identified a partial small bowel obstruction.
- The obstruction was attributed to a proximal ileal neoplasm.
Implications:
- This case highlights a rare gastrointestinal complication of CLL.
- Ileal neoplasms should be considered in CLL patients presenting with obstructive symptoms.
- Early diagnosis and management are crucial for favorable outcomes.
Abstract:
We report the case of a 56-year-old male with a history of chronic lymphocytic leukemia (CLL), RAI 0 and Binet Stage A in therapeutic abstention, who presented to the Emergency Department with a two-week history of low abdominal pain and constipation. Physical examination was unremarkable except for mild diffuse abdominal pain on palpation. Laboratory studies revealed lymphocytosis and anemia (Hb: 10.2 g/dl). An abdominal computed tomography (CT) scan showed a partial small bowel obstruction secondary to a proximal ileal neoplasm.
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