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Pulmonary Malakoplakia Associated with Peripheral Cysts in an Immunocompetent Patient: A Case Report
Liana Ferreira Corrêa1, Thiago Krieger Bento da Silva2, Spencer Marcantonio Camargo3
1Department of Pulmonology, Hospital Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, Brasil.
Insights
Pulmonary malakoplakia, a rare lung condition, was diagnosed in an immunocompetent patient presenting with a unique nodule. This case highlights the need for histopathological examination due to its resemblance to malignant neoplasms.
Area of Science:
- Pulmonology
- Pathology
- Rare Diseases
Background:
- Pulmonary malakoplakia is an uncommon lung condition.
- It predominantly affects immunocompromised individuals.
- Differential diagnosis often includes malignant neoplasms.
Observation:
- This study details a rare case of pulmonary malakoplakia in a young, immunocompetent patient.
- The patient presented with an irregular pulmonary nodule featuring peripheral cysts.
- Surgical intervention preceded the definitive diagnosis.
Findings:
- The case represents the first published description of pulmonary malakoplakia presenting with peripheral cysts.
- Histopathological examination was crucial for accurate diagnosis, distinguishing it from cancerous growths.
- The condition's rarity and atypical presentation posed diagnostic challenges.
Implications:
- This case expands the known clinical spectrum of pulmonary malakoplakia.
- It underscores the importance of considering rare diagnoses in pulmonary nodule evaluation.
- Accurate histopathological diagnosis is essential for appropriate patient management.
Abstract:
Pulmonary malakoplakia is a rare lung lesion more frequently found in immunocompromised patients than in immunocompetent individuals. In this study, we report the challenging case of a young immunocompetent patient with an irregular pulmonary nodule with peripheral cysts who, after undergoing surgery, was diagnosed with malakoplakia. Due to the rarity of the disease and the similarity of this condition to malignant neoplasms, cytopathological or histopathological examinations are necessary for the correct diagnosis. A description of pulmonary malakoplakia with peripheral cysts has not been previously published in the literature.
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