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Updated: Aug 25, 2025
Intravital Subcellular Microscopy of the Mammary Gland
Published on: June 24, 2022
Thirteenth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer
Alecia-Jane Twigger1,2, Jakub Sumbal3,4,5, Mohamed Bentires-Alj6
1Department of Pharmacology, University of Cambridge, Cambridge, UK.
Insights
The European Network for Breast Development and Cancer (ENBDC) workshop reunited scientists to discuss mammary gland biology and breast cancer research, sharing the latest unpublished findings and cutting-edge methods.
Area of Science:
- Mammary Gland Biology
- Breast Cancer Research
Background:
- The European Network for Breast Development and Cancer (ENBDC) Laboratories Annual Workshop reconvened in person in 2022 after a pandemic-induced hiatus.
- The workshop focused on advancing methods in mammary gland biology and breast cancer research.
Purpose of the Study:
- To share the latest research findings and unpublished work in mammary gland biology and breast cancer.
- To foster collaboration and discuss cutting-edge methodologies among 60 participating scientists.
Main Methods:
- Presentations of recent findings through oral and poster sessions.
- Discussions on diverse topics including lactation, embryonic development, single-cell sequencing, and advanced imaging techniques.
- Exploration of breast cancer research areas such as DCIS progression, endocrine therapy resistance, lobular breast cancer models, and cancer risk associated with mutational landscapes.
Main Results:
- The workshop facilitated the exchange of novel, unpublished data from leading researchers.
- Key areas of focus included single-cell sequencing of the human breast and advanced imaging of mammary glands.
- Significant progress was presented in understanding breast cancer progression, treatment resistance, and risk factors.
Conclusions:
- The ENBDC workshop successfully brought together experts to advance the fields of mammary gland biology and breast cancer.
- The event highlighted the importance of interdisciplinary collaboration and the sharing of cutting-edge research and methodologies.
- Continued research is crucial for understanding and combating breast cancer, from early development to treatment resistance.
Abstract:
The thirteenth annual workshop of the European Network for Breast Development and Cancer (ENBDC) Laboratories Annual Workshop took place on the 28-30 April 2022 in Weggis, Switzerland and focused on methods in mammary gland biology and breast cancer. Sixty scientists participated in the ENBDC annual workshop which had not been held in person since 2019 due to the global COVID-19 pandemic. Topics spanned the mammary gland biology field, ranging from lactation biology and embryonic development, single cell sequencing of the human breast, and stunning cutting-edge imaging of the mouse mammary gland and human breast as well as breast cancer research topics including invasive progression of the pre-invasive DCIS stage, metabolic determinants of endocrine therapy resistance, models for lobular breast cancer, and how mutational landscapes of normal breast during age and pregnancy determine cancer risk. The latest findings from participating researchers were presented through oral presentations and poster sessions and included plenty of unpublished work.
