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Splenic epidermoid cyst in a dog
Nayoung Lee1, Dae-Yong Kim1, Yeon-Jung Kim2
1Department of Veterinary Pathology and Research Institute of Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
Insights
A rare splenic epidermoid cyst was identified in a dog, marking the first reported case in animals. This finding expands our understanding of splenic cysts and their potential occurrence beyond humans.
Area of Science:
- Veterinary Pathology
- Comparative Pathology
- Surgical Pathology
Background:
- Splenic epithelial cysts are exceptionally rare in human medicine.
- To date, no splenic epithelial cysts have been documented in animal species.
- The spleen is a vital organ in the canine immune system, with various neoplastic and non-neoplastic conditions.
Abstract:
Splenic epithelial cysts are rare in humans and have not been reported in animals, to our knowledge. During a routine medical examination of a 12-y-old castrated male Maltese dog, a splenic mass was found and subsequently removed via splenectomy. Histologically, a well-defined multilocular cyst in the spleen was lined mostly by simple cuboidal, multifocally by stratified cuboidal, or occasionally by stratified squamous epithelium. Immunohistochemically, the lining cells were positive for cytokeratin and negative for vimentin, CD31, and Wilms tumor protein 1. The case was diagnosed as a primary splenic epidermoid cyst.
