The Endoscopic Endonasal Dacryocystorhinostomy (eDCR) in the Immunocompromised Patient

G Lunardi1,2, P Schiavo2, R Amadori3

  • 1Piazza Principessa Clotilde 3, 20121 Milan, Italy Department of Otolaryngology, Ospedale Fatebenefratelli E Oftalmico, Università Degli Studi Di Milano.

Insights

This case study details managing a patient with common variable immunodeficiency (CVID) and chronic dacryocystitis. An endoscopic endonasal dacryocystorhinostomy was successfully performed, highlighting a unique surgical approach for complex lacrimal sac issues.

Area of Science:

  • Ophthalmology
  • Immunology
  • Otolaryngology

Background:

  • Common Variable Immunodeficiency (CVID) can present with complex sinonasal and orbital manifestations.
  • Chronic dacryocystitis and lacrimal sac empyema pose significant management challenges, especially in immunocompromised patients.
  • Limited literature exists on managing dacryocystitis in patients with CVID, necessitating careful diagnostic and therapeutic evaluation.

Purpose of the Study:

  • To present a clinical case of a patient with CVID and recurrent dacryocystitis.
  • To describe the diagnostic and therapeutic approach for complex lacrimal sac pathology in an immunocompromised patient.
  • To discuss the rationale behind the chosen surgical technique and management strategy.

Main Methods:

  • Endoscopic endonasal dacryocystorhinostomy using "cold" instruments.
  • Radiological evaluation for accurate diagnosis.
  • Management balancing post-surgical follow-up with pandemic-related infectious risks.
  • Consideration of oral and topical therapies to prevent infectious complications.

Main Results:

  • Successful endoscopic endonasal dacryocystorhinostomy with no immediate post-surgical complications.
  • Patient management adapted to minimize infectious risk during a pandemic.
  • Discussion of surgical technique, avoidance of prostheses, and therapeutic strategies.

Conclusions:

  • Endoscopic endonasal dacryocystorhinostomy with "cold" instruments is a viable option for CVID patients with complex dacryocystitis.
  • Careful pre-operative evaluation and tailored post-operative management are crucial.
  • Balancing necessary medical care with infectious risk mitigation is essential in immunocompromised patients, particularly during public health crises.

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