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Crystal-storing histiocytosis and associated marginal zone lymphoma with extensive plasmacytic differentiation

Ayah Al-Qaderi1, Ali Sakhdari1

  • 1Department of Laboratory Medicine and Pathobiology Toronto General Hospital, University Health Network Toronto Ontario Canada.

Clinical Case Reports
|May 23, 2023
PubMed

Insights

Crystal-storing histiocytosis (CSH) is a non-cancerous condition where cells build up immunoglobulin crystals. CSH can hide underlying B-cell lymphomas and plasma cell cancers, requiring careful tissue examination.

Area of Science:

  • Pathology
  • Hematology
  • Oncology

Background:

  • Crystal-storing histiocytosis (CSH) is characterized by intracellular immunoglobulin crystal accumulation within histiocytes.
  • CSH is often linked to lymphoproliferative disorders, particularly B-cell lymphomas and plasma cell neoplasms.

Keywords:
crystal‐storinghistiocytosisimmunoglobulinlymphoma

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